TY - JOUR AU - Stefanowski, Nataniel AU - Tkachenko, Halyna AU - Kurhaluk, Natalia PY - 2021/05/31 Y2 - 2024/03/28 TI - Evaluation of the Antibacterial Activity of Ethanolic Extracts Obtained from Roots and Stalks of Chelidonium majus L. against Escherichia coli Strains JF - Agrobiodiversity for Improving Nutrition, Health and Life Quality JA - – 1 –Agrobiodivers Improv Nutr Health Life Qua VL - 5 IS - 1 SE - Articles DO - UR - https://agrobiodiversity.uniag.sk/scientificpapers/article/view/360 SP - AB - <p style="text-align: justify;">Nowadays, antibiotic resistance among pathogenic bacteria is increasingly common. The <em>Chelidonium majus</em> L. is one of the most widely used genera in folk medicine, where it is popular for its antibacterial activity. The purpose of this study was to evaluate the antimicrobial effects of five ethanolic extracts obtained from stalks and roots of <em>C. majus</em> collected from the rural and urban agglomerations on the territory of the Kartuzy district in the Pomeranian province (northern part of Poland) against <em>Escherichia coli</em> strains. The <em>Escherichia coli</em> (Migula) Castellani and Chalmers (ATCC® 25922™) and <em>Escherichia coli</em> Castellani and Chalmers (ATCC® 25922™) strains were used in the current study. It has been observed that ethanolic extracts derived from stalks and roots of <em>C. majus</em> collected from rural and urban areas revealed weak antibacterial activity (7.95–8.25 mm as the diameters of inhibition zone) compared to the control samples. Our results revealed that the extracts derived from stalks and roots of <em>C. majus</em> have shown weak antibacterial activity against the tested strains. The detailed chemistry of the active compounds and possible mechanism(s) of actions of the bio-molecules responsible for the observed activity was not addressed in the current study. Thus, further evaluation for the nature of active compounds (bio-molecules) and detailed mechanism(s) of their interaction with microbial strains are recommended.</p> ER -