The influence of Helicobacter pylori strains leads to changes in lipid profile and content of the adhesion molecules in patients with gastric ulcer and duodenal ulcer in combination with diabetes and hypertension type 2. Correction which is carried out antihacker drugs and a diet that includes flax seed, which has not only the function of healing, but also improve lipid metabolism and antioxidant effect. The purpose of this study was to evaluate the vascular endothelial function in patients with peptic ulcer of stomach and duodenal ulcers combined with arterial hypertension and diabetes mellitus type 2 with subsequent correction. Considering the change of the disturbances of lipid profile and content of the adhesion molecules in addition to offered diet in this disease it is necessary to take flax seeds in the form of tinctures, fruit drinks etc. The main properties of which is to improve peristalsis, the saturation of the organism with various amino acids, manganese, potassium, magnesium and essential fatty acids omega-3, omega-6 and omega-9. Lignans present in the shell and play the role of antioxidant system and reduce cholesterol with long-term administration. The increasing of insulin secretion and the development of atherosclerotic process due to increased LDL synthesis, which is regulating by the enzyme lopreato (LPL), reduces the concentration of HDL. Minimally oxidized LDL increased expression of adhesion molecules (ICAM, VCAM). Therefore, the pathogenetic relationship of Helicobacter pylori with the development of hypertension and type 2 diabetes patients PWS and DPK will reveal the initial changes of the vessels and the endothelium that will help you effectively choose treatment.